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Table 2 Non-synonymous nucleotide changes reported in published mtDNAs with m.4171C>A

From: Association of the mtDNA m.4171C>A/MT-ND1 mutation with both optic neuropathy and bilateral brainstem lesions

Case Origin Haplogroup Non-synonymous nucleotide changesa Reference
1 Korea A 4171A, 4824, 8794, 14766 [9]
2 Korea A 4171A [9]
3 China n.a. n.a. [10]
4 China N9a1 4171A, 10203 b,,12358, 14564 b, 14766, 14841 c, 15095 [11]
5 France J2b1 4171A, 4216, 7632 c, 10398, 13708, 14766, 15257, 15452A, 15812 [8]
6 Belarus H 4171A, 4705 b, 5263 b, 14180 b Present study
  1. aThe non-synonymous nucleotide changes at nps 8860 (8860G) and 15326 (15326G), present in all sequenced samples, are not included because they are private mutations of the reference sequence.7 In Italics, variants outside of their usual mtDNA background: b)variants in Complex I subunits or c)variants outside in Complex I subunits.