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Table 2 Five year prevalence estimates for different measures (2000–2005) for musculoskeletal, cardiovascular and mental disorders among MS patients and the general population, with incidence rates (IRs) for DP per 100 000 person-years and adjusted odds ratios (ORs) with 95% confidence intervals (CIs)

From: Co-morbidities increase the risk of disability pension among MS patients: a population-based nationwide cohort study

 

MS -patients

General Population

MS patients vs. General population (All)d

MS patients vs. General population (at risk for DP)d

All (n = 10 791)

At risk for DP (n = 4 519)

All (n = 5 618 191)

At risk for DP (n = 4 972 174)

Model 1 b

%

%

IRs

%

%

IRs

Adj ORs

CI 95%

Adj ORs

CI 95%

Musculoskeletal disorders

          

Yes

43.5

33.8

88.2

22.1

19.7

15.1

2.21

(2.11-2.28)

1.91

(1.79-2.03)

No

  

56.4

  

3.5

    

Cardiovascular disorders

          

Yes

24.8

15.4

90.5

14.6

12.4

15.7

1.42

(1.36-1.49)

1.34

(1.23-1.46)

No

  

62.6

  

4.4

    

Mental disorders

          

Yes

43.5

29.4

109.6

15.5

12.1

25.2

3.37

(3.24-3.50)

2.59

(2.43-2.77)

No

  

51.1

  

3.2

    

Model 2 a

          

Musculoskeletal disorders

          

Yes

22.0

18.7

81.9

15.6

13.6

17.8

1.25

(1.19-1.31)

1.37

(1.27-1.48)

No

  

63.3

  

3.9

    

Cardiovascular disorders

          

Yes

12.2

8.0

85.1

6.9

5.5

19.6

1.47

(1.39-1.57)

1.55

(1.39-1.67)

No

  

65.1

  

5.0

    

Mental disorders

          

Yes

11.7

10.3

99.8

8.9

7.1

27.7

1.20

(1.13-1.27)

1.31

(1.19-1.44)

No

  

62.8

  

4.2

    

Model 3 c

          

Musculoskeletal disorders (exl. ATC: M01, M03)

          

Yes

24.1

19.7

82.0

16.5

14.3

17.7

1.31

(1.26-1.37)

1.40

(1.30-1.50)

No

  

63.0

  

3.8

    

Mental disorders (exl. ATC:N06AB, N05c)

          

Yes

35.8

22.1

110.1

13.9

10.7

26.0

2.80

(2.69-2.91)

2.03

(1.89-2.18)

No

  

55.8

  

3.4

    
  1. aPrevalence estimates are based on sick-leave (MiDAS) and on in- and out-patient ICD-10 diagnoses (PAR); M00-M99, I00-I99 and F00-F99.
  2. bPrevalence estimates are based on sick-leave (MiDAS) and on in- and out-patient ICD-10 diagnoses (PAR); M00-M99, I00-I99 and F00-F99, and the following ATC-codes (PDR); M01-M09. C01-C10 and N05-N06.
  3. cPrevalence estimates are based on the same criteria as the model 1, except that hypnotics and sedatives (ATC: N05C), centrally acting sympathomimetics (N06BA) anesthetics (M01), and muscle relaxants (M03) are excluded from the case definition.
  4. dAll analyses are adjusted for gender and age-groups. In the models the general population is coded as the reference category, i.e. ORs >1 indicate that MS-patients are more likely to have a particular type of disorder.
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BMC Neurology

ISSN: 1471-2377

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