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Table 4 logistic regression analysis for the association of renal indicators and cerebral microbleeds

From: Cystatin C, a novel indicator of renal function, reflects severity of cerebral microbleeds

     Model 1    Model 2      
Variables Unadjusted OR 95% CI p Adjusted OR 95% CI p Adjusted OR 95% CI p Adjusted OR   p
Log-Cystatin C, per SD* 1.37 1.18-1.59 <0.01 1.30 1.05-1.69 0.02 1.27 1.04-1.61 0.02 1.73 1.82-3.08 <0.01
Log-albumin/Creatinine, per SD 0.90 0.81-1.01 0.08 0.90 0.82-1.03 0.93     1.00 0.87-1.14 0.96
Estimated GFR*, per SD 1.01 0.64-0.91 <0.01 1.01 0.82-1.30 0.80 1.01 0.80-1.27 0.86    
  1. *SD; standard deviation, GFR; glomerular filtration rate.
  2. Model 1: Estimated GFR and log transformed cystatin C, and microalbumin/creatinine ratios were analyzed separately in an individual ordinal logistic model.
  3. Model 2: the first ordinal logistic regression analysis was performed using log transformed value of cystatin C and estimated GFR together. The second model used log transformed values of cystatin C and microalbumin/creatinine ratios as variables. All models were adjusted for covariates: age, sex, total cholesterol, diabetes, hypertension, dyslipidemia, previous heart disease, smoking, previous anti thrombotic or anticoagulant use, and white matter lesions.