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Table 1 Schedule of assessments

From: Long term cerebral and vascular complications after irradiation of the neck in head and neck cancer patients: a prospective cohort study: study rationale and protocol

Assessment

Baseline

Follow-up

Demographics

  

Worksituation

 

X

Education

 

X

Marital status

 

X

Social/living status

 

X

Oncologic diagnose

X

X

Radiotherapy

  

Dosis Total (Gy)

X

X

Dosis per fraction (Gy)

X

X

Number of fractions

X

X

Bilateral/unilateral

X

X

Dose on common carotid artery

X

X

Dose on internal carotid artery

X

X

Medical history

  

Cerebrovascular events

X

X

Cerebrovascular risk factors

X

X

Cardiovascular events

 

X

Hypertension

X

X

Hypercholostrolemia

 

X

Smoking

X

X

Diabetes

 

X

Family history of cerebrovascular disease

 

X

Obesity

 

X

Migraine

 

X

Medication use

  

Aspirin

 

X

Oral anticoagulance

 

X

Antihypertensive medication

 

X

Statin

 

X

Anti-diabetic medication

 

X

Physical examination

  

Length and weight

 

X

Waist circumference

 

X

Blood pressure

X

X

BMI

 

X

Neurological examination

  

Cranial nerves

 

X

Muscle strength

 

X

Coordination

 

X

Mobility

  

Time up and Go/Tinetti

 

X

ECG

  

Paroxysmal atrial fibrillation

 

X

Left ventricle hypertrophia

 

X

Ischemia

 

X

Fasting laboratory investigation

  

Glucose

 

X

Total cholesterol

 

X

Ultrasonography

  

IMT

X

X

Elastography

 

X

Neuropsychological Examination

  

Global cognitive functioning

  

Minimal Mental State Examination (MMSE)

 

X

Frontal Assessment Battery (FAB)

 

X

 1. Episodic Memory

  

Rey Auditory Verbal Learning Test (RAVLT)

 

X

 2. Working memory

  

Paper and Pencil Memory Scanning Tasks

 

X

Digit Span test

 

X

 3. Executive functioning

  

Stroop Color-Word Task

 

X

Trail Making Test (TMT)

 

X

Brixton Spatial Anticipation Test

 

X

 4. Attention

  

Verbal Series Attention Test(VSAT)

 

X

 5. Fluency Language

  

Letter fluency

 

X

Animal fluency

 

X

 6. Speed information processing

  

TMT A

 

X

Stroop test (mean score Parts I and II)

 

X

Letter Digity Substitution Task

 

X

Questionnaires

  

Depressive symptoms

  

Structured questionnaire depressive symptoms

 

X

Mini International Neuropsychiatric Interview (MINI)

 

X

Hospital Anxiety and Depression Scale (HADS)

 

X

Center of Epidemiological Studies Depression scale

 

X

Fatigue

  

CIS 20 R

 

X

Health related Quality of Life

  

Short form36

 

X

Others

  

Structured questionnaire about sleep disorders

 

X

Subjective memory complaints

 

X

MRI

  

Brain (T1, T2, FLAIR)

 

X

Carotid arteries (TOF, PCA, T1, T2, PD)

 

X