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Figure 2 | BMC Neurology

Figure 2

From: Βeta-fibrinogen gene promoter A −455 allele associated with poor longterm survival among 55–71 years old Caucasian women in Finnish stroke cohort

Figure 2

The effect of FGB -455G/A genotype-by-smoking interaction adjusted for elevated CRP on overall post stroke survival (all cause death endpoint) in the 55–71 year old women of the SAM cohort. Survival curves were obtained by Kaplan-Meyer log rank analysis showed poorer longterm survival in the 55–71 year old women who smoked (p = 0.002). Hazard ratios and 95% confidence intervals were obtained by Cox regression forced model adjusted for elevated CRP and the progressive effect of smoking and FGB −455 G/A polymorphism on worse survival was observed ( GG smokers, adjusted HR: 9.83, 95% CI 1.20-80.1; GA/AA non-smokers, adjusted HR: 15.4, 95% CI 1.91-124; GA/AA smokers, adjusted HR: 24.9, 95% CI 3.00-206).

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BMC Neurology

ISSN: 1471-2377

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