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Table 2 Clinical profiles of patients with Kii ALS/PDC and other types of dementia

From: Neuropsychological study of amyotrophic lateral sclerosis and parkinsonism-dementia complex in Kii peninsula, Japan

 

Kii-ALS/PDC (n = 13)

AD (n = 12)

PSP (n = 10)

FTLD (n = 10)

DLB (n = 10)

Sex (male/female)

6/7

4/8

6/4

4/6

4/6

Age at examination, y

69.5 ± 4.5

67.3 ± 5.4

71.3 ± 4.8

66.3 ± 9.0

68.9 ± 5.3

(58–78)

(60–75)

(63–79)

(58–84)

(60–75)

Duration of the disorder, y

4.9 ± 1.6

2.5 ± 0.4*

2.0 ± 1.5*

2.4 ± 1.4*

3.3 ± 1.2

Duration of the cognitive impairement, y

2.6 ± 1.1

2.5 ± 0.4

2.0 ± 1.5

2.1 ± 1.2

2.4 ± 1.1

Education, y

9.9 ± 1.9

11.6 ± 3.2

10.7 ± 3.2

11.0 ± 2.6

11.5 ± 2.6

Clinical features (%)

     

Halluciantion

38

0*

0*

0*

80*

Abulia-apathy

62

0*

50

30

30

Slowing of psychomotor speed

84

42

70

20*

70

Personality changes

77

58

80

80

60

Decrease of extraversion

77

50

80

80

60

Alteration of personarity

0

17*

10

70*

10

Inapproriate social behavior/disinhibition

0

8

0

30*

0

Aphasia

0

0

0

30*

0

  1. *P < 0.05 compared with Kii ALS/PDC patients. Abbreviations: ALS amyotrophic lateral sclerosis, PDC parkinsonism-dementia complex, AD Alzheimer’s disease, PSP progressive supranuclear palsy, FTLD frontotemporal lobar degeneration, DLB dementia with Lewy bodies.