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Table 2 Clinical profiles of patients with Kii ALS/PDC and other types of dementia

From: Neuropsychological study of amyotrophic lateral sclerosis and parkinsonism-dementia complex in Kii peninsula, Japan

  Kii-ALS/PDC (n = 13) AD (n = 12) PSP (n = 10) FTLD (n = 10) DLB (n = 10)
Sex (male/female) 6/7 4/8 6/4 4/6 4/6
Age at examination, y 69.5 ± 4.5 67.3 ± 5.4 71.3 ± 4.8 66.3 ± 9.0 68.9 ± 5.3
(58–78) (60–75) (63–79) (58–84) (60–75)
Duration of the disorder, y 4.9 ± 1.6 2.5 ± 0.4* 2.0 ± 1.5* 2.4 ± 1.4* 3.3 ± 1.2
Duration of the cognitive impairement, y 2.6 ± 1.1 2.5 ± 0.4 2.0 ± 1.5 2.1 ± 1.2 2.4 ± 1.1
Education, y 9.9 ± 1.9 11.6 ± 3.2 10.7 ± 3.2 11.0 ± 2.6 11.5 ± 2.6
Clinical features (%)      
Halluciantion 38 0* 0* 0* 80*
Abulia-apathy 62 0* 50 30 30
Slowing of psychomotor speed 84 42 70 20* 70
Personality changes 77 58 80 80 60
Decrease of extraversion 77 50 80 80 60
Alteration of personarity 0 17* 10 70* 10
Inapproriate social behavior/disinhibition 0 8 0 30* 0
Aphasia 0 0 0 30* 0
  1. *P < 0.05 compared with Kii ALS/PDC patients. Abbreviations: ALS amyotrophic lateral sclerosis, PDC parkinsonism-dementia complex, AD Alzheimer’s disease, PSP progressive supranuclear palsy, FTLD frontotemporal lobar degeneration, DLB dementia with Lewy bodies.