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Table 3 Comparison of prediction performance between the SITS SICH risk score and the extended risk score

From: Oxfordshire community stroke project classification improves prediction of post-thrombolysis symptomatic intracerebral hemorrhage

  Odds ratio (95% CI) per point Hosmer-Lemeshow statistic P AUC (95% CI) Difference between areas P Net reclassification improvement P
SICH per NINDS        
  SITS SICH risk score 1.35 (1.11-1.64) 1.72 0.887 0.624 (0.533-0.714) - - - -
  Extended risk score 1.30 (1.15-1.46) 4.30 0.745 0.704 (0.618-0.791) 0.081 0.015 22.3% 0.011
SICH per ECASS II        
  SITS SICH risk score 1.34 (1.08-1.68) 3.25 0.661 0.612 (0.503-0.721) - - - -
  Extended risk score 1.30 (1.13-1.49) 4.23 0.752 0.703 (0.611-0.796) 0.091 0.016 21.2% 0.018
SICH per SITS-MOST        
  SITS SICH risk score 1.49 (1.14-1.94) 2.10 0.835 0.678 (0.563-0.793) - - - -
  Extended risk score 1.33 (1.12-1.58) 6.45 0.488 0.723 (0.622-0.824) 0.044 0.293 24.5% 0.024
  1. AUC indicates area under the receiver operating characteristic curve; CI: confidence intervals; ECASS: The European-Australasian Cooperative Acute Stroke Study; NINDS: National Institute of Neurological Disorders and Stroke; SICH: symptomatic intracerebral hemorrhage; SITS-MOST: the Safe Implementation of Thrombolysis in Stroke - Monitoring Study.