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Table 3 Subgroup of ischaemic strokes or TIA stratified by age groups (demographic characteristics, risk factors, and stroke subtypes)

From: Lessons from everyday stroke care for clinical research and vice versa: comparison of a comprehensive and a research population of young stroke patients

 

Total groups

 

Age 18-34 years

 

Age 35-44 years

 

Age 45-55 years

 
 

sifap1 (n = 4467)

GQH (n = 14522)

sifap1 (n = 563) 12.6%

GQH (n = 1049) 7.2%***

sifap1 (n = 1224) 27.4%

GQH (n = 2962) 20.4%***

sifap1 (n = 2680) 60%

GQH (n = 10511) 72.4%***

Sex (males); (n = 4467, Sifap1)

59.4%

61.2%*

42.8%

46.3%

57.9%

57.9%

63.5%

63.5%

Age (years); mean, median and 25th-75th percentile (n = 4467, Sifap1)

44.747 (40-51)

47.5*** 50 (44-53)

28.329 (25-32)

28.4 29 (25-32)

40.541 (38-43)

40.6 41 (39-43)

50.150 (47-53)

51.4*** 51 (48-53)

Previous cerebrovascular event (n = 4466, Sifap1)

16.9%

11.9%***

12.8%

7.7%**

15.4%

8.2%***

18.6%

13.3%***

Proportion of TIA (n = 4467, Sifap1)

24.0%

36.4%***

21.8%

41.5%***

25.1%

39.7%***

23.9%

34.9%***

Vascular risk profile

        

 Hypertension (n = 4439, Sifap1)

46.6%

49.5%**

13.1%

11.6%

36.7%

31.7%**

58.2%

58.2%

 Diabetes mellitus (n = 4443, Sifap1)

10.3%

14.4%***

2.0%

3.1%

7.7%

8.6%

13.3%

17.1%***

 Current smoking (n = 4466, Sifap1)

42.5%

40.8%*

37.5%

33.5%

42.1%

41.3%

43.8%

41.5%

Stroke subtypes according to TOAST

n = 4345

n = 14169

n = 555

n = 1006

n = 1201

n = 2902

n = 2589

n = 10261

 Atherosclerosis

16.4%

22.3%***a

4.1%

8.8%***a

10.4%

13.6%***a

21.8%

26%***a

 Cardiac embolic source

15.1%

12.1%

18.6%

15.3%

17.7%

13.4%

13.2%

11.4%

Small artery occlusion

13.7%

19.2%

6.3%

8.2%

9.5%

13.7%

17.2%

21.8%

 Other determined cause

16.5%

9.8%

24.5%

16.7%

20.8%

14.3%

12.8%

7.8%

 Undetermined cause

38.3%

36.7%

46.5%

51.0%

41.6%

45.0%

34.9%

33.0%

  1. *p < 0.05.
  2. **p < 0.01.
  3. ***p < 0.001.
  4. athe test statistic was calculated by using all five TOAST classification categories.