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Table 2 Clinical and imaging predictors of concomitant CM among DVA cases

From: The association between cerebral developmental venous anomaly and concomitant cavernous malformation: an observational study using magnetic resonance imaging

Characteristics

Total N

CM N (%)

Non CM N (%)

P-value

Unadjusted OR†(95% CI§)

P value

Adjusted OR‡(95% CI§)

P-value

Overall

N = 1839

N = 205

N = 1634

     

Age

.

    

.

  

Median (IQR), years

41.5(29–52)

39(27–49)

42(29–52)

0.0242

    
    

0.2299

    

<20

210

25(11.9%)

185(88.1%)

 

1.0

.

1.0

.

20- 39

617

80(13%)

537(87%)

 

1.10(0.68–1.78)

0.6899

1.06(0.65–1.72)

0.2037

40-59

801

82(10.2%)

719(89.8%)

 

0.84(0.52–1.36)

0.4848

0.85(0.53–1.39)

0.6832

> = 60

211

18(8.5%)

193(91.5%)

 

0.69(0.36–1.31)

0.2555

0.72(0.38–1.38)

0.2760

Gender

.

  

0.0241

 

.

  

Female

899

85(9.5%)

814(90.5%)

 

1.0

.

1.0

.

Male

940

120(12.8%)

820(87.2%)

 

1.40(1.04–1.88)

0.0246

1.30(0.97–1.76)

0.0839

DVA Location

.

  

<.0001

 

.

  

Supratentorial

1319

121(9.2%)

1198(90.8%)

 

1.0

.

1.0

.

Infratentorial

520

84(16.2%)

436(83.8%)

 

1.91(1.41–2.57)

0.0000

1.71(1.26–2.33)

0.0006

DVA imaging

.

  

<.0001

 

.

  

Medullary veins ≥ 3

1451

128(8.8%)

1323(91.2%)

 

1.0

.

1.0

.

Medullary veins<3

388

77(19.8%)

311(80.2%)

 

2.56(1.88–3.48)

0.0000

2.37(1.73–3.24)

0.0000

Quantity of DVAs

.

  

0.0470

 

.

  

Single

1782

194(10.9%)

1588(89.1%)

 

1.0

.

1.0

.

Multiple

57

11(19.3%)

46(80.7%)

 

1.96(1.00–3.84)

0.0510

2.08(1.04–4.16)

0.0384

  1. OR: odds ratio, CI: confidence interval, IQR: inter-quartile range.
  2. †Unadjusted odds ratios and p-values generated via univariate analysis.
  3. ‡Adjusted odds ratios and p-values resulted from multivariate analysis using a logistic regression model. All variables in univariate analysis were included in the multivariable model.
  4. §All CI presented are 95% CI and all p-values presented are two-sided.