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Table 3 Comparison of previous studies on CD58 – MS/NMO association

From: CD58 polymorphisms associated with the risk of neuromyelitis optica in a Korean population

Reference

Study populations

Study subjects

Study allele

  

(case/control)

rs12044852

rs1335532

rs2300747

   

P-value(OR)

P-value(OR)

P-value(OR)

Hafler et al. (2007) [13]

US and UK (MS)

2322/5418 (1540 family trios)

1.9 × 10 −5 (1.24)

-

-

Rubio et al. (2008) [16]

Australia (MS)

1134/1265

0.042 (1.20)

-

-

Bahlo et al. (2009) [18]*

Australia, NZ, UK, and US (MS)

3874/5723

-

9.6 × 10 −8 (1.28)

-

De Jager et al. (2009) [17]*

US, UK, Belgium, Japanese, Chinese, and Finland (MS)

3558/4420 (1768 family trios)

-

-

1.1 × 10 −6 (1.22)

Brynedal et al. (2009) [28]*

Swedish (MS)

1077/1217

4.3 × 10 −4 (1.39)

-

-

Qiu et al. (2013) [29]

Australia (MS)

350/498

-

-

0.093 (1.56)

Present study

Korean (NMO)

99/237

0.004 (1.80)

0.002 (1.87)

0.007 (1.73)

  1. *Since these studies had reversed minor and major alleles compared to the present study, we modified their results to conform to our results. Italicized P-values are values below 0.05, which indicate significance.