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Table 3 EDSS and MSFC as primary or secondary outcome in relevant clinical trials*

From: Systematic literature review and validity evaluation of the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Functional Composite (MSFC) in patients with multiple sclerosis

 

Start of study

 
 

1990 - 2000

2000 – today

Total

EDSS

13

37

50

  Primary outcome

10

17

27

  Secondary outcome

3

20

23

MSFC

-

9

9

  Primary outcome

-

1

1

  Secondary outcome

-

8

8

  1. *Not taken into account is that the EDSS is in addition to the primary outcome used as secondary outcome. In this overview, only a classification in the “higher” endpoint occurs.