Table 3 Neuropsychological test results of the iNPH patient subgroups by CSF Aβ42 level before CSF drainage (N = 18, A) and change before and after CSF drainage (N = 10, B)
(A) | (B) | |||||
|---|---|---|---|---|---|---|
Lower CSF Aβ42 | Higher CSF Aβ42 | P | Lower CSF Aβ42 | Higher CSF Aβ42 | p | |
(n = 7) | (n = 11) | (n = 5) | (n = 5) | |||
Attention | ||||||
Digit span forward test | 4.7 ± 1.1 | 6.2 ± 1.4 | 0.018* | 0.2 ± 1.3 | -0.6 ± 0.8 | 0.131 |
Digit span backward test | 2.0 ± 1.5 | 2.7 ± 1.1 | 0.271 | 0.0 ± 0.7 | -0.2 ± 0.8 | 0.911 |
Language function | ||||||
K-BNT | 25.3 ± 6.6 | 36.1 ± 14.3 | 0.157 | 2.4 ± 6.5 | 0.6 ± 3.6 | 0.602 |
Visuospatial function | ||||||
RCFT Copy | 12.8 ± 10.7 | 23.7 ± 12.5 | 0.043* | 0.1 ± 4.5 | -1.0 ± 2.1 | 0.577 |
Memory function | ||||||
SVLT immediate recall | 6.8 ± 1.9 | 13.3 ± 3.6 | 0.009* | 2.0 ± 3.0 | 4.2 ± 3.8 | 0.117 |
SVLT delayed recall | 0.1 ± 0.3 | 1.8 ± 2.0 | 0.204 | 0.0 ± 0.0 | 2.0 ± 1.8 | 0.054 |
SVLT recognition | 15.5 ± 2.9 | 15.9 ± 4.0 | 0.820 | -1.0 ± 4.1 | 1.4 ± 2.8 | 0.602 |
RCFT immediate recall | 2.9 ± 4.3 | 7.9 ± 6.7 | 0.129 | -0.8 ± 2.5 | 2.2 ± 3.5 | 0.245 |
RCFT delayed recall | 1.8 ± 2.8 | 6.6 ± 6.2 | 0.232 | 0.3 ± 2.3 | 3.0 ± 3.2 | 0.245 |
RCFT recognition | 16.0 ± 3.3 | 16.9 ± 3.1 | 0.480 | -2.6 ± 3.2 | 2.0 ± 3.0 | 0.465 |
Frontal function | ||||||
Contrasting program | 15.0 ± 8.3 | 14.2 ± 9.1 | 0.691 | -0.2 ± 0.4 | 0.2 ± 0.4 | 0.180 |
Go-no go | 9.6 ± 10.2 | 11.0 ± 9.1 | 0.499 | 3.2 ± 8.9 | 2.8 ± 6.2 | 0.451 |
Semantic COWAT | 6.3 ± 3.9 | 8.8 ± 6.1 | 0.269 | -1.4 ± 3.3 | 5.4 ± 6.1 | 0.117 |
Phonemic COWAT | 10.0 ± 6.0 | 14.4 ± 11.4 | 0.926 | -1.0 ± 1.7 | 5.4 ± 6.1 | 0.018* |
Stroop test: color reading | 26.0 ± 13.2 | 44.5 ± 35.9 | 0.905 | -4.4 ± 9.5 | 8.2 ± 8.1 | 0.008* |