From: Clinical analysis of adult-onset spinocerebellar ataxias in Thailand
 | SCA1 | SCA2 | MJD | SCA6 | p-value* |
---|---|---|---|---|---|
Total numbers | 21 | 15 | 39 | 8 | Â |
Sex (M/F) | 11/10 | 8/7 | 14/25 | 4/4 | 0.500 |
Age at onset (years) | Â | Â | Â | Â | Â |
 Mean age at onset | 38.43 | 41.47 | 39.97 | 43.5 | 0.715 |
 SD | 10.14 | 13.01 | 12.17 | 6.76 |  |
 Range | 15 – 55 | 19 - 60 | 16 - 64 | 34 - 58 |  |
Duration (years) | Â | Â | Â | Â | Â |
 Mean duration | 5.43 | 3.93 | 6.62 | 6 | 0.328 |
 SD | 5.13 | 2.99 | 5.01 | 5.90 |  |
 Range | 1 - 20 | 1 - 10 | 0.25 - 22 | 1 - 18 |  |
Positive family history (%) | 16 (76.2) | 13 (86.7) | 32 (82.1) | 7 (87.5) | 0.900 |
CAG repeat size (repeats) | Â | Â | Â | Â | Â |
 Mean | 50.14 | 37.40 | 69.97 | 21.88 |  |
 SD | 6.27 | 4.47 | 4.04 | 0.83 |  |
 Range | 41 – 65 | 32 - 52 | 62 - 78 | 21 - 23 |  |
Clinical features (%) | Â | Â | Â | Â | Â |
 Slow saccade | 12 (57.1) | 7 (46.7) | 21 (53.9) | 2 (25) | 0.454 |
 Horizontal nystagmus | 5 (23.8) | 4 (26.7) | 34 (87.2) | 6 (75) | 0.0000002** |
 Vertical nystagmus | 0 (0) | 1 (6.7) | 6 (15.4) | 3 (37.5) | 0.026** |
 Opthalmoparesis | 6 (28.6) | 3 (20.0) | 26 (66.7) | 2 (25) | 0.002** |
 Pale optic disc | 1 (4.8) | 0 (0) | 2 (5.1) | 1 (12.5) | 0.610 |
 Hyperreflexia | 19 (90.5) | 5 (33.3) | 26 (66.7) | 7 (87.5) | 0.002** |
 Babinski’s sign | 11 (52.4) | 5 (33.3) | 17 (43.6) | 5 (62.5) | 0.510 |
 Areflexia | 0 (0) | 5 (35.7) | 9 (23.1) | 0 (0) | 0.011** |
 Sensory impairment | 4 (19.0) | 3 (20.0) | 9 (23.1) | 0 (0) | 0.630 |
 Parkinsonism | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1.000 |
 Dystonia | 1 (4.8) | 0 (0) | 1 (2.6) | 0 (0) | 0.475 |
 Chorea | 0 (0) | 0 (0) | 1 (2.6) | 0 (0) | 1.000 |
 Dementia | 0 (0) | 1 (6.7) | 0 (0) | 1 (12.5) | 0.074 |
 Facial fasciculation | 2 (9.5) | 0 (0) | 5 (12.8) | 0 (0) | 0.579 |
SARA | Â | Â | Â | Â | Â |
 Mean scale | 16.97 | 13.18 | 16.76 | 15.71 | 0.767 |
 SD | 7.45 | 3.66 | 7.27 | 7.24 |  |
 Range | 4 - 30 | 9 - 20 | 8 - 35 | 3.5 - 27 |  |