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Table 2 Florbetapir SUVr for selected cortical regions by diagnostic group

From: PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer’s disease and Lewy body disorders

 

HC

PD

AD

DLB

P value

Pair-wise comparison*

Average of cortical regions

1.02 (0.096)

1.12 (0.249)

1.53 (0.184)

1.32 (0.285)

0.0047

b,d

Frontal cortex

0.91 (0.046)

0.98 (0.219)

1.34 (0.204)

1.15 (0.285)

0.0059

b,d

Temporal cortex

1.06 (0.080)

1.11 (0.197)

1.57 (0.191)

1.37 (0.283)

0.0030

b,d

Parietal cortex

0.98 (0.097)

1.01 (0.335)

1.42 (0.188)

1.21 (0.235)

0.0111

b,f

Anterior cingulate

1.00 (0.087)

1.14 (0.241)

1.62 (0.245)

1.32 (0.345)

0.0038

b,d,f

Posterior cingulate

1.03 (0.125)

1.14 (0.312)

1.47 (0.212)

1.38 (0.300)

0.0131

b,c,d

Precuneus

1.16 (0.192)

1.30 (0.302)

1.77 (0.219)

1.51 (0.353)

0.0057

b,d

  1. *a = HC vs. PD; b = HC vs. AD; c = HC vs. DLB; d = PD vs. AD; e = PD vs. DLB; f = AD vs. DLB.
  2. Mean SUVr values (and SD) are given for each group. P-values are for the overall group comparison from Kruskal-Wallis test. Subsequent pair-wise comparisons are noted by the letters in the last column if the overall comparison was significant at p < 0.05.