Donepezil effect on life expectancy in AD. DNP = donepezil, AD = Alzheimer’s disease. The vertical line indicates life expectancy (months). There was a significant drug effect (F = 14.497; p < 0.001) with a significant covariate effect of nursing home residency (F = 18.167. p < 0.001). No other covariates reached a significant level (age: F = 0.075, p = 0.785; gender: F = 0.171, p = 0.680; CVD: F = 3.827, p = 0.054; typical antipsychotic drugs: F = 0.353, p = 0.554; atypical antipsychotic drugs: F = 0.583, p = 0.447).