Table 2 NQO1 rs1800566 genotype and allelic variants of patients with multiple sclerosis (MS) and healthy volunteers
From: NQO1gene rs1800566 variant is not associated with risk for multiple sclerosis
MS PATIENTS N (%, 95% C.I.) | CONTROLS N (%, 95% C.I.) | Intergroup comparison values OR (%, 95% C.I.) P | MS WOMEN N (%, 95% C.I.) | CONTROL WOMEN N (%, 95% C.I.) | Intergroup comparison values OR (%, 95% C.I.) P | MS MEN N (%, 95% C.I.) | CONTROL MEN (N (%, 95% C.I.) | Intergroup comparison values OR (95% CI) P | |
|---|---|---|---|---|---|---|---|---|---|
rs1800566 GENOTYPE C/C | 178 (61.4, 55.8-67.0) | 195 (62.9, 57.5-68.3) | Reference | 120 (60.0, 53.2-66.8) | 134 (62.9, 56.4-69.4) | Reference | 58 (64.4, 54.6-74.3) | 61 (62.9, 53.3-72.5) | Reference |
C/T | 99 (34.1, 28.7-39.6) | 104 (33.5, 28.3-38.8) | 1.43 (0.74-1.47), 0.810 | 72 (36.0, 29.3-42.7) | 72 (33.8, 27.5-40.2) | 1.12 (0.74-1.68), 0.597 | 27 (30.0, 20.5-39.5) | 32 (33.0, 23.6-42.3) | 0.88 (0.48-1.66), 0.708 |
T/T | 13 (4.5, 2.1-6.9) | 11 (3.5, 1.5-5.6) | 1.30 (0.57-2.96), 0.540 | 8 (4.0, 1.3-6.7) | 7 (3.3, 0.9-5.7) | 1.28 (0.45-3.63), 0.646 | 5 (5.6, 0.8-10.3) | 4 (4.1, 0.2-8.1) | 1.32 (0.34-5.14), 0.693 |
Total | 290 | 310 | 200 | 213 | 90 | 97 | |||
Allele C | 455 (78.4, 75.1-81.8) | 494 (79.7, 76.5-82.8) | Reference | 312 (78.0, 73.9-82.1) | 340 (79.8, 76.0-83.6) | Reference | 143 (79.4, 73.5-85.3) | 154 (79.4, 73.7-85.1) | Reference |
Allele T | 125 (21.6, 18.2-24.9) | 126 (20.3, 17.2-23.5) | 1.08 (0.82-1.42), 0.601 | 88 (22.0, 17.9-26.1) | 86 (20.2, 16.4-24.0) | 1.12 (0.80-1.56), 0.523 | 37 (20.6, 14.7-26.5) | 40 (20.6, 14.9-26.3) | 1.00 (0.60-1.65), 0.988 |
Total alleles | 580 | 620 | 400 | 426 | 180 | 194 |