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Table 1 Characteristics of patients at the time of enrollment in the trials

From: To what degree does cognitive impairment in Alzheimer's disease predict dependence of patients on caregivers?

Characteristic   All Patients Supervision per day Dependence Level
    ≤ 12 hrs > 12 hrs < 3 ≥ 3
Number   1287 407 880 692 595
Socio-demographic details
Age, (years) Mean (SD) 73.8 (8.3) 72.9 (8.5) 74.2 (8.2)* 72.1 (8.6) 75.8 (7.5)*
Female N (%) 801 (62) 261 (64.1) 540 (61.4) 388 (56.1) 413 (69.4)*
Education beyond elementary school N (%) 876 (68.8) 271 (67.6) 605 (69.3) 508 (74.1) 368 (62.6)*
Lives with caregiver N (%) 934 (74.2) 203 (51.5) 731 (84.5)* 496 (73.0) 438 (75.5)
Spouse or partner caregiver N (%) 781 (62.1) 175 (43.0) 606 (68.9)* 431 (62.3) 350 (58.8)
Clinical characteristics
Time since onset of cognitive problems, (years) Mean (SD) 3.8 (2.6) 3.6 (2.6) 3.9 (2.6)* 3.7 (2.6) 4.0 (2.6)*
Time since AD diagnosis (years) Mean (SD) 1.0 (1.4) 0.9 (1.2) 1.1 (1.4) 0.9 (1.3) 1.1 (1.4)*
Extra-pyramidal symptoms N (%) 68 (5.2) 15 (3.7) 53 (6.0) 29 (4.2) 39 (6.6)
Anti-psychotic medication N (%) 328 (25.5) 81 (19.9) 247 (28.1)* 134 (19.3) 194 (32.6)*
MMSE Mean (SD) 19.3 (3.7) 20.4 (3.4) 18.8 (3.8)* 20.5 (3.3) 18.0 (3.8)*
ADAS-cog Mean (SD) 25.4 (10.4) 22.7 (9.7) 26.7 (10.5)* 22.0 (8.7) 29.5 (10.8)*
Dependence
Dependence level >= 3 N (%) 583 (46.0) 134 (32.9) 461 (52.4)   
DAD Mean (SD) 70.1 (22.5) 77.7 (20.0) 66.7 (22.7)* 81.9 (14.9) 56.3 (22.0)*
  1. * Statistically significant difference between groups (p = 0.05).