Number
| |
1287
|
407
|
880
|
692
|
595
|
Socio-demographic details
|
Age, (years)
|
Mean (SD)
|
73.8 (8.3)
|
72.9 (8.5)
|
74.2 (8.2)*
|
72.1 (8.6)
|
75.8 (7.5)*
|
Female
|
N (%)
|
801 (62)
|
261 (64.1)
|
540 (61.4)
|
388 (56.1)
|
413 (69.4)*
|
Education beyond elementary school
|
N (%)
|
876 (68.8)
|
271 (67.6)
|
605 (69.3)
|
508 (74.1)
|
368 (62.6)*
|
Lives with caregiver
|
N (%)
|
934 (74.2)
|
203 (51.5)
|
731 (84.5)*
|
496 (73.0)
|
438 (75.5)
|
Spouse or partner caregiver
|
N (%)
|
781 (62.1)
|
175 (43.0)
|
606 (68.9)*
|
431 (62.3)
|
350 (58.8)
|
Clinical characteristics
|
Time since onset of cognitive problems, (years)
|
Mean (SD)
|
3.8 (2.6)
|
3.6 (2.6)
|
3.9 (2.6)*
|
3.7 (2.6)
|
4.0 (2.6)*
|
Time since AD diagnosis (years)
|
Mean (SD)
|
1.0 (1.4)
|
0.9 (1.2)
|
1.1 (1.4)
|
0.9 (1.3)
|
1.1 (1.4)*
|
Extra-pyramidal symptoms
|
N (%)
|
68 (5.2)
|
15 (3.7)
|
53 (6.0)
|
29 (4.2)
|
39 (6.6)
|
Anti-psychotic medication
|
N (%)
|
328 (25.5)
|
81 (19.9)
|
247 (28.1)*
|
134 (19.3)
|
194 (32.6)*
|
MMSE
|
Mean (SD)
|
19.3 (3.7)
|
20.4 (3.4)
|
18.8 (3.8)*
|
20.5 (3.3)
|
18.0 (3.8)*
|
ADAS-cog
|
Mean (SD)
|
25.4 (10.4)
|
22.7 (9.7)
|
26.7 (10.5)*
|
22.0 (8.7)
|
29.5 (10.8)*
|
Dependence
|
Dependence level >= 3
|
N (%)
|
583 (46.0)
|
134 (32.9)
|
461 (52.4)
| | |
DAD
|
Mean (SD)
|
70.1 (22.5)
|
77.7 (20.0)
|
66.7 (22.7)*
|
81.9 (14.9)
|
56.3 (22.0)*
|