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Table 1 Characteristics of patients at the time of enrollment in the trials

From: To what degree does cognitive impairment in Alzheimer's disease predict dependence of patients on caregivers?

Characteristic

 

All Patients

Supervision per day

Dependence Level

   

≤ 12 hrs

> 12 hrs

< 3

≥ 3

Number

 

1287

407

880

692

595

Socio-demographic details

Age, (years)

Mean (SD)

73.8 (8.3)

72.9 (8.5)

74.2 (8.2)*

72.1 (8.6)

75.8 (7.5)*

Female

N (%)

801 (62)

261 (64.1)

540 (61.4)

388 (56.1)

413 (69.4)*

Education beyond elementary school

N (%)

876 (68.8)

271 (67.6)

605 (69.3)

508 (74.1)

368 (62.6)*

Lives with caregiver

N (%)

934 (74.2)

203 (51.5)

731 (84.5)*

496 (73.0)

438 (75.5)

Spouse or partner caregiver

N (%)

781 (62.1)

175 (43.0)

606 (68.9)*

431 (62.3)

350 (58.8)

Clinical characteristics

Time since onset of cognitive problems, (years)

Mean (SD)

3.8 (2.6)

3.6 (2.6)

3.9 (2.6)*

3.7 (2.6)

4.0 (2.6)*

Time since AD diagnosis (years)

Mean (SD)

1.0 (1.4)

0.9 (1.2)

1.1 (1.4)

0.9 (1.3)

1.1 (1.4)*

Extra-pyramidal symptoms

N (%)

68 (5.2)

15 (3.7)

53 (6.0)

29 (4.2)

39 (6.6)

Anti-psychotic medication

N (%)

328 (25.5)

81 (19.9)

247 (28.1)*

134 (19.3)

194 (32.6)*

MMSE

Mean (SD)

19.3 (3.7)

20.4 (3.4)

18.8 (3.8)*

20.5 (3.3)

18.0 (3.8)*

ADAS-cog

Mean (SD)

25.4 (10.4)

22.7 (9.7)

26.7 (10.5)*

22.0 (8.7)

29.5 (10.8)*

Dependence

Dependence level >= 3

N (%)

583 (46.0)

134 (32.9)

461 (52.4)

  

DAD

Mean (SD)

70.1 (22.5)

77.7 (20.0)

66.7 (22.7)*

81.9 (14.9)

56.3 (22.0)*

  1. * Statistically significant difference between groups (p = 0.05).