Table 4 Outcome Measures.
From: Deflazacort for the treatment of Duchenne Dystrophy: A systematic review
Outcome Measure | Description | Used in Study |
|---|---|---|
Direct Strength Measures | ||
Myometer | Isometric force of quadriceps femoris muscle at 90° measured in kg. [32] | B |
MRC score | The sum of MRC scale in four muscles. Two in the right upper extremity and two in the right lower extremity. Maximum score 20. [32] | A, G |
MRC index | The MRC score divided by the maximum possible score of 20 then multiplied by 100 to give a percentage representation of the MRC score. [32] | B |
Average muscle score | Called Strength score in previous trials.[33] This is the mean grade of 34 tested muscles on a ten point scale (modified from the MRC system). | N |
Functional Measures | ||
Timed gait | Number of seconds needed to walk for 10 metres. | A, B |
Timed stairs | Number of seconds needed to walk up four stairs. | A, B |
Timed chair | Number of seconds needed to rise from seated in a chair to standing. | A, B |
Timed Gower | Number of seconds needed to rise from a sitting position on the floor to standing. | A, B |
Graded gait | A score assigned for 10 m of walking. Points assigned for increasing dysfunction for a range between zero and seven. [32] | A, B |
Graded stairs | A score assigned for walking up four stairs. Points assigned for increasing dysfunction with a range between zero and seven. [32] | A, B |
Graded chair | A score assigned for rising from a chair to standing. Points assigned for increasing dysfunction with a range between zero and six. [32] | A, B |
Graded Gower | A score assigned for rising from a sitting position to standing. Points assigned for increasing dysfunction with a range between zero and seven. [32] | A, B |
Others | ||
Patient reported benefit | No description of measure available. | F |
Time to loss of ambulation | Measured in months. | B |