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Table 5 Strength Outcomes. Studies Comparing Deflazacort and Prednisone.

From: Deflazacort for the treatment of Duchenne Dystrophy: A systematic review

Study (Duration of Follow up) A. Bonifati, 2000 (12 months) F. Angelini, 1998 (12 months) N. Brooke, 1996 (3 months)
Strength Measures
MRC score * (mean change in score from baseline) DFZ: + 1 Pred: + 0.5 No variance or P values reported. - -
Average Muscle score * (mean change in score from baseline) - - DFZ (low): +0.18 (+/- 0.4) DFZ (high): +0.26 (+/- 0.5) Pred: +0.27 (+/- 0.5) Standard errors imputed from p values.
Functional Measures
Timed gait Measured but not reported. - -
Timed stairs - - -
Timed chair - - -
Timed Gower - - -
Graded gait ** DFZ: - 0.5 Pred: -0.5 Combined score from all four tests. No variance or p values reported. - -
Graded stairs ** - - -
Graded chair ** - - -
Graded Gower ** - - -
Other Measures
Patient reported benefit - Patients reported benefit on both prednisone and DFZ. No numeric representation of reported benefit was reported. -
  1. A dash represents that this outcome measure was not used. MRC = Medical Research Council * For MRC score, MRC index and muscle score higher scores are more favorable. ** For Graded scores a lower score is more favorable.