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Table 3 Patients (%) with global perceived effect on pain in the four arms of treatment and totals for the two treatments.

From: Randomised controlled trial of gabapentin in Complex Regional Pain Syndrome type 1 [ISRCTN84121379]

Treatment period

GBP-1=

Placebo-1=

Wash-out=

GBP-2=

Placebo-2=

% some improvement (n)

45% (10)

13% (3)

1

8% (2)

13% (3)

% much improvement (n)

14% (3)

5% (1)

0

21% (5)

4% (1)

% total (n/N)

59% (13/22)

a 17% (4/24)

1

29% (7/24)

18% (4/22)

=

Total = GBP =

=

Total = placebo =

=

=

% some improvement

26% (12/46)

 

13% (6/46)

  

% much improvement

17% (8/46)β

 

4% (2/46)

  

% total (n/N)

43% (20/46)a

 

17% (8/46)

  

worsened

13% (6/46)

 

9% (4/46)

  
  1. GBP-1 is gabapentin treatment before wash-out. GBP-2 is gabapentin treatment after wash-out. 'α' is significant, P < 0.005, 'β' is P < 0.10 McNemar two sided tested gabapentin versus placebo.