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Figure 5 | BMC Neurology

Figure 5

From: Homozygosity for a missense mutation in the 67 kDa isoform of glutamate decarboxylase in a family with autosomal recessive spastic cerebral palsy: parallels with Stiff-Person Syndrome and other movement disorders

Figure 5

Three illustrations of the genomic, protein and comparative sequence homologies of the different species of GAD.(A) The genomic structures of GAD1/GAD 25 /GAD2 and Drosophila Gad1. (B) Comparative protein domain structures of GAD65/GAD25/GAD67 and Drosophila Gad1. (Numbers represent approximate amino acid residues). (C) Schematic illustrating the relative homology of the protein structures of GAD67/GAD65 and Drosophila Gad1.

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