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Figure 2 | BMC Neurology

Figure 2

From: Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

Figure 2

Effects of MC IV dosing on infarct size at 24 hr after 90 min TMCAO. The post hoc tests for the proportion infarct size showed that within the 4-hour administration time, the 3 mg/kg (p = 0.0001) and 10 mg/kg (p = 0.0001) minocycline groups had significantly lower mean proportion infarct size than the saline group. At the 5-hour administration time, the 3 mg/kg (p = 0.0010) and 10 mg/kg (p = 0.0002) minocycline groups had significantly lower mean proportion infarct size than the saline group. There were no statistically significant differences in the proportion infarct size between treatment groups at the 6-hour administration time window * the number atop the bar figure was the animal numbers of that group.

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