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Table 2 Proton magnetic resonance spectroscopic imaging voxel metabolite value and metabolite ratio (Mean +/- SD) of control subjects and patients with multiple sclerosis (NAWM vs. Control and WML vs. Control p > 0.05; * p < 0.05 vs. NAWM)

From: Magnetic resonance spectroscopy of normal appearing white matter in early relapsing-remitting multiple sclerosis: correlations between disability and spectroscopy

value

Control

NAWM

WM lesion

NAA

106.1 +/- 20.9

102.23 +/- 20.2

102.61 +/- 29.9

Cr

61.7 +/- 13.0

62.13 +/- 14.2

63.94 +/- 13.0

mI

36.67 +/- 4.9

39.32 +/- 10.9

39.39 +/- 8.3

Cho

53.6 +/- 17.0

54.77 +/- 16.5

51.06 +/- 13.1

NAA/Cr

1.73 +/- 0.24

1.67 +/- 0.18

1.6 +/- 0.22

Cho/Cr

0.86 +/- 0.11

0.89 +/- 0.19

0.80 +/- 0.15*

mI/Cr

0.61 +/- 0.11

0.63 +/- 0.10

0.62 +/- 0.12

  1. NAA: N acetylaspartate; Cr: Creatine; mI: Myoinositol; Cho: choline; NAWM: normal appearing white matter; WML: white matter lesions
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BMC Neurology

ISSN: 1471-2377

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