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Table 4 Genotype frequencies of the EBF1 polymorphism in HLA-DRB1*1501 positive and negative multiple sclerosis patients.

From: Early B-cell Factor gene association with multiple sclerosis in the Spanish population

EBF rs1368297

AA

AT

TT

A

T

DRB1*1501+ MS patients*

51

53

19

155

91

(n = 123)

41.5%

43.1%

15.4%

63%

37%

DRB1*1501- MS patients

74

115

39

263

193

(n = 228)

32.5%

50.4%

17.1%

57.7%

42.3%

Controls

149

267

108

565

483

(n = 524)

28.4%

50.9%

20.6%

53.9%

46.1%

  1. * AA vs. (AT+TT): p = 0.005; OR (95% CI) = 1.78 (1.16–2.73)
  2. A vs. T: p = 0.01; OR (95% CI) = 1.46 (1.08–1.96)