Table 2 Yields of proteins identified in each cohort and group. A total of 73 proteins were identified from the 3 pooled HC, CFS and PGI specimens of cohort 1. Twenty proteins were shared by the CFS and PGI specimens that were absent from the pooled HC sample. This was the cohort 1 pooled CFS – related proteome. Cohort 2 consisted of 12 HC and 9 CFS individuals. A total of 113 proteins were identified, with 16 identified by multilinear regression (general linear model, GLM) as the cohort 2 CFS – related proteome. When the proteins from all of the specimens were examined, a set of 19 out of 115 proteins were significantly different between HC and CFS by ANOVA.
From: A chronic fatigue syndrome – related proteome in human cerebrospinal fluid
Cohort 1 (pooled samples) | Cohort 2 (individual samples) | All specimens | |||||
|---|---|---|---|---|---|---|---|
Protein yield per cohort | 73 | 113 | 115 | ||||
Groups in each cohort | HC | CFS | PGI | HC | CFS | HC | CFC |
Samples per group | 1 | 1 | 1 | 12 | 9 | 13 | 11 |
Proteins per group | 17 | 63 | 40 | 71 | 82 | 72 | 83 |
Proteins shared within cohorts | 12 | 12 | 12 | 39 | 39 | 40 | 40 |
Proteins unique to each group | 2 | 28 | 8 | 32 | 43 | 32 | 43 |
CFS-related proteomes | 20 | 16 | 19 | ||||
Statistical method | Matching | GLM | ANOVA | ||||