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Table 2 Yields of proteins identified in each cohort and group. A total of 73 proteins were identified from the 3 pooled HC, CFS and PGI specimens of cohort 1. Twenty proteins were shared by the CFS and PGI specimens that were absent from the pooled HC sample. This was the cohort 1 pooled CFS – related proteome. Cohort 2 consisted of 12 HC and 9 CFS individuals. A total of 113 proteins were identified, with 16 identified by multilinear regression (general linear model, GLM) as the cohort 2 CFS – related proteome. When the proteins from all of the specimens were examined, a set of 19 out of 115 proteins were significantly different between HC and CFS by ANOVA.

From: A chronic fatigue syndrome – related proteome in human cerebrospinal fluid

  Cohort 1 (pooled samples) Cohort 2 (individual samples) All specimens
Protein yield per cohort 73 113 115
Groups in each cohort HC CFS PGI HC CFS HC CFC
Samples per group 1 1 1 12 9 13 11
Proteins per group 17 63 40 71 82 72 83
Proteins shared within cohorts 12 12 12 39 39 40 40
Proteins unique to each group 2 28 8 32 43 32 43
CFS-related proteomes   20   16   19
Statistical method Matching GLM ANOVA