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Table 3 Chronic fatigue syndrome – associated cerebrospinal fluid proteomes. Proteins from the cohort 1 – and cohort 2 – related CFS proteomes (+) or not part of these proteomes (0) were shown in columns 2 and 3. The 5 proteins from cohort 2 that were most predictive of CFS (80% concordance) were defined by the "biosignature variable"B 1/5 (right justified and bold italics). The 2 cohorts were combined (n = 24 samples) and the frequencies of detection in all control (HC, n = 13) and CFS (n = 11) samples compared by ANOVA and Fisher's Exact Test. NCBI accession numbers (gi|) were given.

From: A chronic fatigue syndrome – related proteome in human cerebrospinal fluid

  Cohort CFS – Associated Proteome (all 24 samples) HC % (n = 13) CFS % (n = 11) ANOVA Fisher's Exact Test
GeneID        
  1 2      
720, 721 + + Complement C4A/B 0% 55% 0.0010 0.0034
2934 + + Gelsolin 0% 45% 0.0046 0.011
3868 0 + Keratin 16 (B 1/5 ) 0% 45% 0.0046 0.011
5176 + + PEDF (B 1/5 ) 0% 45% 0.0046 0.011
3537 0 0 Ig λ 15% 64% 0.014 n.s.
351 + + APLP1 0% 36% 0.016 0.031
1356 + + Ceruloplasmin 0% 36% 0.016 0.031
2 + + α-2-Macroglobulin (B 1/5 ) 0% 36% 0.016 0.031
5005 + + Orosomucoid 2 (B 1/5 ) 0% 36% 0.016 0.031
5168 + + Autotaxin 0% 36% 0.016 0.031
1114 0 0 Chromogranin B 0% 36% 0.016 0.031
63827 + + BEHAB (B 1/5 ) 0% 36% 0.016 0.031
12 + 0 α-1-Antichymotrypsin 8% 45% 0.034 n.s.
3240 + 0 Haptoglobin 15% 55% 0.044 n.s.
3263 0 0 Hemopexin 15% 55% 0.044 n.s.
6696 0 0 Secreted phosphoprotein 1 0% 27% 0.046 n.s.
3872 0 + Keratin 17 0% 27% 0.046 n.s.
140446 0 + Keratin 6C 0% 27% 0.046 n.s.
718 + 0 Complement C3 23% 64% 0.047 n.s.