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Table 1 Clinical characteristics of the patients

From: Dose-dependent improvement of myoclonic hyperkinesia due to Valproic acid in eight Huntington's Disease patients: a case series

Patient Sex CAG AO Motoric AO Psychic Duration TFC IS % Rigidity Swallowing problems
Case 1 M 22/46 28 22 11 2 20 ++ +++
Case 2 F 20/54 37 ND 6 5 70 + -
Case 3* M 17/48 23 23 8 3 40 ++ ++
Case 3* M 17/48 23 23 12 2 30 ++ +++
Case 4 M 19/48 33 ND 11 4 40 +++ ++
Case 5 M 17/43 50 45 6 3 40 ++ ++
Case 6 F 25/52 31 ND 10 3 40 ++ ++
Case 7 F 17/50 28 26 7 6 70 + -
Case 8 M 17/50 30 30 11 3 30 +++ +++
  1. Clinical characteristics of the patients. AO = age of onset, TFC = Total functional capacity (UHDRS), IS = Independence score (UHDRS), CAG = CAG-ranges (low/high); Intensity: - = none, + = mild, ++ = moderate, +++ = severe. ND = no data. One patient (*) was treated twice with an increased dose of valproic acid within a 4 year period, see text.