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Table 2 T2 lesion load and brain fractional volume (Mean [SEM]).

From: Monthly intravenous methylprednisolone in relapsing-remitting multiple sclerosis - reduction of enhancing lesions, T2 lesion volume and plasma prolactin concentrations

 

Baseline period

Treatment period

 

Month 1

Month 6

Change (mth 6 vs. mth 1)

Month 7

Month 12

Change (mth 12 vs. mth 7)

Change (mth 12 vs. mth 6)

T2 lesion load (ml)

19.93 [4.8]

22.49 [4.64]

+ 13 %

p < 0.001

20.68 [4.23]

17.70 [4.17]

- 14 %

p = 0.001

- 21%

p = 0.001

BFV (%)

86.4 [1.4]

86.1 [1.8]

- 0.35 %

n.s.

85.9 [1.9]

83.9 [1.8]

-2.33 %

n.s.

-2.56%

n.s.

  1. Multivariate Wilk's test for T2 lesion load, p = 0.002, and for BFV, p = 0.086; p values given in the table are for univariate F tests.