Table 1 Key information from the community-based neuropathological studies of old age dementia
Study | Hisayama study | CC75C | Vantaa 85+ | CFAS | HAAS | Cache County study | |
|---|---|---|---|---|---|---|---|
Nottingham Gwynedd Newcastle Cambridgeshire Oxford | Liverpool* | ||||||
Start date | 1985 (for dementia prevalence) | 1985–1987 | 1991 | 1991–93 | 1989–91 | 1991–1993 | 1995–1997 |
Number of subjects eligible | 1440 in 1992 | 2,835 | 601 | 16,261 | 6,028 | 4,678 | 5,677 |
Years for re-examination | yearly | 1988–90 1991–92 1994–95 1998–99 2002–2003 | 1994 1996 1999 | 1992 1995 1998 2000 2002 | 1991–93 1997–98 1999 2002 | 1994–1996 1997–1999 2000–2001 2002–2003 2004- in progress | 1998–2000 2004- in progress |
Number of subjects followed initially (% of those eligible) | 1436 (99.7%) in 1992 | 2609 (92%) | 553 (92%) | 13009 (80%) | 5222 (87%) | 3734 (79.8%) | 5092 (89.7%) |
Age at start of study, mean (range) in years | Men 73 (65–92) Women 74 (65–98) | 81 (75–106) | 89 (85–90+) | 75 (65–105)^ | 79 (65–108) | 78 (71–93) | 74 (65–90+) |
% men at start of study | 40 | 34 | 21 | 40 | 47 | 100 | 42 |
Number of brains collected | 176 (1985–1992) + 105 (1998–2001) | 225 (as of mid 2004) | 305 (as of 2002) | 370 | 103 (as of mid 2004) | 559 (as of 2004) | 65 (+5 whom have not completed clinical assessment) (as of 2002) |