Table 5 Meta-analysis of the H63D variation in the five published studies regarding Alzheimer's disease
AD | H63D | Â | |||||
|---|---|---|---|---|---|---|---|
| Â | Patients | Controls | Â | ||||
Author | wt/wt | wt/mut | mut/mut | wt/wt | wt/mut | mut/mut | p |
Moalem, S. [22] | 20 (76.9%) | 6 (23.1%) | 0 | 67 (72%) | 23 (24.8%) | 3 (3.2%) | Â |
Candore, G. [21] | 94 (76.4%) | 24 (19.5%) | 5 (4.1%) | 122 (80.3%) | 26 (17.1%) | 4 (2.6%) | Â |
Berlin, D. [12] | 67 (67%) | 29 (29%) | 4 (4%) | 66 (66%) | 30 (30%) | 4 (4%) | Â |
Sampietro, M. [24] | 85 (79.4%) | 20 (18.7%) | 2 (1.9%) | 74 (74.7%) | 24 (24.3%) | 1 (1%) | Â |
Robson, KJ. [25] | 138 (72.2%) | 50 (26.2%) | 3 (1.6%) | 194 (72.1%) | 67 (24.9%) | 8 (3%) | Â |
Total | 404 | 129 | 14 | 523 | 170 | 20 | 0.96 |