From: Impact of the clinical context on the 14-3-3 test for the diagnosis of sporadic CJD
14-3-3 result | Age at onset, years | Survival time, months | Time from onset to LP, months | Time from LP to death, months | PSWCs in EEG, % | M129V, % |
---|---|---|---|---|---|---|
Positive | 69.8 (45.1–86.9), n= 144 | 4.7 (0.5–48.8), n= 138 | 2.6 (0.7–27.2), n= 125 | 1.2 (0–30.8), n= 119 | 83.9%, n= 112 | 68.0%MM, 15.5%MV, 16.5%VV, n= 103 |
Negative | 73.4 (59.1–82.3), n= 21 | 5.4 (0.4–29.9), n= 15 | 2.9 (0.2–13.9), n= 17 | 1.3 (0–26.8), n= 14 | 81.8%, n= 22 | 80.0%MM, 20.0%MV, 0%VV, n= 15 |