Skip to main content

Table 3 Age at onset, survival time, lumbar puncture (LP) timing, presence of PSWCs in EEG, and genotype at codon 129 of PRNP gene of 14-3-3-positive and 14-3-3-negative sCJD f patients

From: Impact of the clinical context on the 14-3-3 test for the diagnosis of sporadic CJD

14-3-3 result Age at onset, years Survival time, months Time from onset to LP, months Time from LP to death, months PSWCs in EEG, % M129V, %
Positive 69.8 (45.1–86.9), n= 144 4.7 (0.5–48.8),
n= 138
2.6 (0.7–27.2),
n= 125
1.2 (0–30.8),
n= 119
83.9%, n= 112 68.0%MM, 15.5%MV, 16.5%VV, n= 103
Negative 73.4 (59.1–82.3), n= 21 5.4 (0.4–29.9),
n= 15
2.9 (0.2–13.9),
n= 17
1.3 (0–26.8), n= 14 81.8%, n= 22 80.0%MM, 20.0%MV, 0%VV, n= 15
  1. sCJD f includes both probable and definite cases. The data of age, survival time, and LP timing correspond to median and range values.