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Table 1 Intraassay and interassay variation of the ratio AUCRC /AU SRC 1

From: Detection of virus-specific intrathecally synthesised immunoglobulin G with a fully automated enzyme immunoassay system

 

semi-automated method

8-point-standard curve BEP2000

4-point-standard curve BEP2000

 

Measles

Rubella

VZV

HSV

Measles

Rubella

VZV

HSV

Measles

Rubella

VZV

HSV

Intraassay

            

n

    

10

10

10

10

10

10

10

10

Mean

n. d.2

n. d.

n. d.

n. d.

0.95

0.92

0.95

0.91

0.89

0.89

0.91

0.91

Standard deviation

n. d.

n. d.

n. d.

n. d.

0.04

0.06

0.04

0.05

0.03

0.01

0.06

0.03

Coefficient of variation

n. d.

n. d.

n. d.

n. d.

4.5%

6.9%

4.5%

5.1%

3.2%

1.6%

6.8%

3.1%

Interassay

            

n

20

19

22

24

10

10

11

11

20

19

23

19

Mean

1.10

1.06

1.04

1.09

0.99

0.97

0.96

0.96

1.05

1.07

1.14

1.06

Standard deviation

0.15

0.11

0.09

0.13

0.05

0.06

0.08

0.07

0.10

0.04

0.07

0.08

Coefficient of variation

14.0%

10.3%

8.9%

12.2%

5.3%

6.2%

8.6%

6.9%

9.6%

4.1%

6.3%

7.3%

  1. 1CRC and SRC represent an artificial serum-CSF-pair available in sufficient quantity to be repeatedly tested. The theoretical value of AUCRC/AUSRC is 1. For further details, see method.
  2. 2 n. d. – not determined
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BMC Neurology

ISSN: 1471-2377

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