Neuropathological findings processed by artificial neural networks (ANNs) can perfectly distinguish Alzheimer's patients from controls in the Nun Study

Table 3 Comparison between severe and non severe AD patients.

Variables	Mean	SD	Mean	SD	p value
Age at last exam.	91.63	5.88	88.69	4.14	n.s.
Education years	15.69	2.81	14.00	3.65	n.s.
ADL	3.23	1.88	0.23	0.83	<0.001
WRCL	0.46	0.78	0.00	0.00	<0.001
CNPR	7.85	2.64	0.54	1.94	<0.001
BOSTON	8.31	2.95	0.31	0.85	<0.001
VRBF	5.92	3.66	0.00	0.00	<0.001
MMSE	15.00	6.36	0.23	0.60	<0.001
Mean NFT neocortex	29.31	17.24	14.74	13.39	<0.001
Mean NFT Hippocampus	50.31	22.99	46.75	25.22	n.s.
Max NP neocortex	11.65	4.81	9.92	3.73	n.s.
Max NP Hippocampus	5.34	4.12	6.71	3.15	n.s.

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