Figure 1
From: Matrix metalloproteinases and their inhibitors in human traumatic spinal cord injury
Distribution of MMPs and TIMPs in the normal human spinal cord. Images were taken from control human spinal cords in transverse sections. A: Immunohistochemistry for MMP-1 revealed cytoplasmic staining in motoneurons; the nucleus was devoid of immunoreactivity. B: Staining for MMP-9 demonstrated a single intravascular monocyte (arrow) within a parenchymal blood vessel. C: The TIMP-2 antibody displayed cytoplasmic immunoreactivity in motoneurons, the nucleus being devoid of staining. D: Immunohistochemistry for TIMP-3 also shows cytoplasmic staining in motoneurons without a nuclear signal. (A-D, mag. ×260)