Figure 5

Diagnostic differentiation of patient with PD vs. APS (MSA & PSP). Postsynaptic radiotracers [18, 28, 34, 35, 37, 46, 50, 53-59]. * follow-up trial. # The pooled odds ratio (95%CI) after excluding the study of Pirker '97 (sensitivity 100%, specificity 0%) did not change significantly: 19 (10–33). Schwarz 1993. this trial can be seen as follow-up trial (long-term l-dopa is golden standard) but also as a cross-sectional trial. In the last case the results will be different (sensitivity = 79%, specificity = 100%). Schwarz 1997: We took signs (in) compatible with PD as golden standard. If taken long-term l-dopa as golden standard sensitivity is 100% and specificity is 67%. Schwarz 1998: We took signs (in) compatible with PD taken as golden standard, if taken long-term-l-dopa as golden standard sensitivity is 100% and specificity is 50%.