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Table 3 Correlation matrix of plasma cortisol concentration versus LPS-stimulated whole blood in vitro cytokine production

From: Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production

  

IL-1β production

IL-6 production

TNF production

  

r

p

r

p

r

p

Control subjects

09:00

-0.09

0.6

-0.001

1.0

-0.39

0.02

 

Admission matched†

0.18

0.3

-0.02

0.9

-0.06

0.7

Patients

Admission

-0.57

< 0.001

-0.59

< 0.001

-0.72

< 0.001

 

24 hours

-0.65

< 0.001

-0.64

< 0.001

-0.67

< 0.001

 

5–7 days

-0.58

0.001

-0.48

0.006

-0.68

< 0.001

 

3 months

-0.05

0.8

-0.13

0.5

-0.10

0.6

 

12 months

-0.35

0.2

-0.09

0.7

-0.17

0.5

  1. r values are Rank Spearman correlation coefficients
  2. †admission matched data includes 09:00 values if admission was between 07:00 and 11:00