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Table 4 Maximum Likelihood estimates (MLE) of the mean profiles, and common of the clinical and neuropsychological assessment variables across the selected three LCs (*)

From: Latent profile analysis in frontotemporal lobar degeneration and related disorders: clinical presentation and SPECT functional correlates

 

Latent class means (#)

 

Variable

LC1 (n = 18)

LC2 (n = 41)

LC3 (n = 38)

Common variances

BADL (lost functions)

2.444

0.366

0.184

1.049

IADL (lost functions)

5.111

1.244

0.632

2.858

NPI

31.556

8.707

11.211

0.847

FBI, A

19.833

7.610

6.289

4.025

FBI, B

14.056

2.122

3.711

1.524

Neuropsychological Assessment

    

MMSE

19.283

20.917

25.790

2.198

Short Story (ES)

0.889

0.537

1.632

1.551

Colored Progressive Matrices (ES)

0.722

0.683

2.632

0.807

Rey Figure, Copy (ES)

0.278

0.585

2.211

2.089

Rey Figure, Recall (ES)

0.333

1.000

2.895

2.116

Fluency, Letter (ES)

1.000

1.000

2.184

2.122

Fluency, Category (ES)

0.222

0.756

2.632

1.279

Digit PNFAn (ES)

2.111

2.220

3.211

2.466

Token Test (ES)

0.722

0.927

2.895

1.682

Trial-Making, Test A (ES)

0.278

0.463

3.158

1.165

Trial-Making, Test B (ES)

0.278

0.366

2.105

1.226

  1. BADL: Basic Activities of Daily Living; IADL: Instrumental Activities of Daily Living; NPI: Neuropsychiatry Inventory; FBI: Frontal Behavioural Inventory. ES: Equivalent Scores (according to Italian normative data, range 0–4; 0 = poor performance to 4 better performance). (*) All MLEs were statistically significant (i.e different to zero using t-test: P < 0.05), and expressed mean values.
  2. (#) Statistically significant (P < 0.05) means differences between LC1 vs. (LC2, LC3) are bold-underline, while between (LC1, LC2) vs. LC3 are underline.