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Table 2 Patient-proxy differences and agreement on baseline and follow-up

From: Longitudinal proxy measurements in multiple sclerosis: patient-proxy agreement on the impact of MS on daily life over a period of two years

 

MSIS-29

Directional differencea (Mean ± SD) (95% CI)

d

ICC (95% CI)

Exact agreement (%)

Global agreement (%)

Baseline (n = 59)

Physical scale

-0.8 ± 15.3 (-4.9 – 3.2)

0.1

0.81 (0.70–0.88)

47.4

83.1

 

Psychological scale

-4.4 ± 17.0 (-8.7 – 0.1)

0.3

0.72 (0.55–0.82)

44.6

82.5

Follow-up (n = 56)

Physical scale

-4.8 ± 12.7b (-8.2 – 1.4)

0.4

0.86 (0.76–0.92)

43.3

82.6

 

Psychological scale

-8.9 ± 18.8b (-14.0 – 3.9)

0.5

0.65 (0.42–0.79)

38.1

81.0

  1. a Patient minus proxy respondent; negative scores indicate that the proxy scores higher than the patient.
  2. b Statistically significant difference between mean score of patient and proxy groups (P < 0.05)
  3. MSIS-29: Multiple Sclerosis Impact Scale, SD: standard deviation, ICC: intraclass correlation coefficient, d: effect size, CI: confidence interval