Table 1 Characteristics of stroke patients by leukoaraiosis.

Age (yr)

72.1 ± 9.8

61.1 ± 11.9

< 0.001

Gender

0.001

   Male (n = 342)

157 (45.9)

185 (54.1)

   Female (n = 252)

150 (59.5)

102 (40.5)

Hypertension (n = 383)

229 (59.8)

154 (40.2)

< 0.001

Diabetes mellitus (n = 236)

133 (56.4)

103 (43.6)

0.390

Hyperlipidemia (n = 193)

95 (49.2)

98 (50.8)

0.228

Heart disease (n = 105)

44 (41.9)

61 (58.1)

0.018

Atrial fibrillation (n = 78)

34 (43.6)

44(56.4)

0.125

Regular cigarette smoking (n = 153)

57 (37.3)

96 (62.7)

< 0.001

Previous ischemic stroke (n = 87)

58 (66.7)

29 (33.3)

0.002

Stroke subtype

0.016

   Large artery disease(n = 297)

170 (57.2)

127 (42.8)

0.031^a

0.006^b

   Lacunar(n = 193)

93 (48.2)

100 (51.8)

0.198^b

   Cardioembolic (n = 104)

44 (42.3)

60 (57.7)