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Table 2 Two-point LOD scores for chromosome 9p21.2-q22.32 markers

From: Pedigree with frontotemporal lobar degeneration – motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9

  

III:8 Affected

III:8 Unaffected

Marker

Location

θ

θ

 

(cM)

0.00

0.20

0.40

0.00

0.20

0.40

D9S259‡

47.19

-2.1

-0.07

0.03

-2.21

-0.09

0.03

D9S169‡

49.20

-0.54

0.53

0.08

-0.99

0.33

0.07

D9S161†

51.81

2.51

1.39

0.26

2.14

1.17

0.20

D9S319‡

54.50

3.25 *

1.96

0.51

2.82

1.70

0.43

D9S1118‡

58.26

1.08

0.59

0.13

1.05

0.57

0.43

D9S304‡

58.26

0.34

0.14

0.01

0.31

0.11

0.00

D9S1845‡

58.80

1.15

1.36

0.37

2.90

1.72

0.44

D9S1817†

59.34

1.47

1.55

0.43

3.24*

1.97

0.53

D9S1805‡

59.34

0.75

1.2

0.26

2.46

1.41

0.30

D9S163‡

59.87

1.34

0.53

0.04

0.94

0.31

0.00

D9S273†

65.79

1.03

1.36

0.37

2.77

1.62

0.40

D9S175†

70.33

0.50

1.01

0.28

2.26

1.40

0.36

D9S167†

83.41

-3.58

-0.30

0.01

-1.85

0.11

0.07

  1. * Peak LOD Scores.
  2. † ABI Prism Linkage Mapping Set markers.
  3. ‡ Marshfield Medical Research Foundation genetic framework markers.
  4. All map distances are derived from the Marshfield Genetic Map except for marker D9S163 that was inferred from the Kong human genetic map. [33]
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BMC Neurology

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