From: Angiotensin-converting enzyme gene insertion/deletion polymorphism in migraine patients
Genotypes | Alleles | |||||
---|---|---|---|---|---|---|
N | DD(%) | ID(%) | II(%) | D(%) | I(%) | |
Controls | 403 | 92 (26.6) | 204 (50.6) | 107 (22.8) | 388 (48.1) | 418 (51.9) |
Migraine | 347 | 78 (22.5) | 186 (53.6) | 83 (23.9) | 342 (49.3) | 352 (50.7) |
MwA subgroup | 155 | 34 (21.9) | 87 (56.1) | 34 (21.9) | 155 (50.0) | 155 (50.0) |
MoA subgroup | 187 | 43 (23.0) | 96 (51.3) | 48 (25.7) | 182 (48.7) | 192 (51.3) |
Lisinopril responders | 12 | 2 (16.7) | 6 (50.0) | 4 (33.3) | 10 (41.7) | 14 (58.3) |
Lisinopril non-responders | 37 | 10 (27.0) | 16 (43.2) | 11 (29.7) | 36 (48.6) | 38 (51.4) |
Candesartan responders* | 18 | 7 (38.9) | 9 (50.0) | 2 (11.1) | 23 (63.9) | 13 (36.1) |
Candesartan non-responders* | 38 | 8 (21.1) | 18 (47.4) | 12 (31.6) | 34 (44.7) | 42 (55.3) |
Responders combined | 30 | 9 (30.0) | 15 (50.0) | 6 (20.0) | 33 (55.0) | 27 (45.0) |
Non-responders combined | 75 | 18 (24.0) | 34 (45.3) | 23 (30.7) | 70 (46.7) | 80 (53.3) |