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Table 1 Clinical characteristics and cardiac function ultrasonographic variables.

From: Plasma brain natriuretic peptide as a surrogate marker for cardioembolic stroke

Variable

Non-Cardioembolic Stroke

(n = 69)

Cardioembolic Stroke

(n = 62)

Age (years)

69.9 ± 9.9

69.8 ± 10.4

Sex, F/M

19/50

24/38

Systolic Blood Pressure (mmHg)

177 ± 11

182 ± 14

Body Mass Index, kg/m2

23.6 ± 2.5

24.1 ± 3.4

Blood Urea Nitrogen, mg/dl

15.2 ± 5.6

13.7 ± 4.3

Creatinine, mg/dl

1.10 ± 0.27

1.06 ± 0.37

Hypertension, yes/no (%)

46/23 (66.7%)

41/21 (66.1%)

Dislipidemia, yes/no (%)

15/54 (21.7%)

16/46 (25.8%)

Diabetes Mellitus, yes/no (%)

17/52 (24.6%)

18/44 (29.0%)

Smoking, yes/no (%)

42/27 (60.9%)

34/28 (54.8%)

Atrial fibrillation (including permanent and paroxysmal Af), yes/no (%)

2/67 (2.9%)

49/13 (79.0%)**

Mitral stenosis, yes/no (%)

0/69 (0%)

3/59 (4.8%)

Mitral regurgitation, yes/no (%)

20/49 (29.0%)

34/28 (54.8%)*

Heart Failure, yes/no (%)

5/64 (7.2%)

9/53 (14.5%)

Old Myocardial Infarction, yes/no (%)

3/66 (4.3%)

8/54 (12.9%)

Cardiomyopathy, yes/no (%)

4/65 (5.8%)

4/58 (6.5%)

Chronic Renal Failure, yes/no (%)

7/62 (10.1%)

5/57 (8.1%)

Plasma BNP (pg/ml)

49.6 ± 43.3

106.6 ± 31.5**

Duration after ischemic onset to BNP measurement (hours)

9.2 ± 4.2

9.6 ± 3.8

NIH Stroke Scale score at admission: median (25%–75%)

11 (9–14)

12 (9–18)

Beta-blocker, yes/no (%)

12/57 (17.4%)

13/49 (21.0%)

Angiotensin receptor blocker, yes/no (%)

36/33 (52.2%)

25/37 (40.3%)

Angiotensin converting enzyme inhibitor, yes/no (%)

7/62 (10.1%)

9/53 (14.5%)

E/A

0.8 ± 0.2

1.7 ± 0.6**

LA diameter (mm)

33.9 ± 5.4

41.6 ± 6.8**

LV end-diastolic diameter (mm)

47.9 ± 2.2

47.8 ± 2.2

LV end-systolic diameter (mm)

28.9 ± 2.3

29.1 ± 2.3

Interventricular septum thickness (mm)

12.2 ± 2.8

12.7 ± 2.8

LV posterior wall thickness (mm)

12.3 ± 2.4

12.8 ± 2.5

LV ejection fraction (%)

62.1 ± 10.0

60.8 ± 13.3

LAA flow (cm/s)

76.6 ± 14.1

35.0 ± 22.0**

  1. LA; left atrium. LV; left ventricular. LAA; left atrial appendage.
  2. *: p < 0.01, **: p < 0.001 compared with patients in non-cardioembolic stroke.
  3. The values in this table: means and standard deviations or medians (ranges of 25 to 75 percentile) are given for the continuous variables; numbers of patients are given for the categorical variables. %: percentile.