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Table 3 MAPT genotypes and haplotypes in patients with FTLD and eoAD

From: Role of MAPT mutations and haplotype in frontotemporal lobar degeneration in Northern Finland

Sample

Genotypes

Haplotypes

 

N

Individuals

H1/H1

N (%)

H1/H2

N (%)

H2/H2

N (%)

Genotype vs. controlsb

N

Alleles

H1

N (%)

H2

N (%)

Haplotypes vs. controls

FTLD

59

47 (79.7)

11 (18.6)

1 (1.7)

P = 0.018a

118

105 (89.0)

13 (11.0)

P = 0.028a

EoAD

122

98 (80.3)

24 (19.7)

0

P = 0.006a

244

220 (90.2)

24 (9.8)

P = 0.029a

Controls

198

180 (90.9)

15 (7.6)

3 (1.5)

 

396

375 (94.7)

21 (5.3)

 
  1. a Indicates statistical significance
  2. b The genotypes were grouped into H1/H1 and H1/H2 + H2/H2 for statistical analysis