From: Role of MAPT mutations and haplotype in frontotemporal lobar degeneration in Northern Finland
Sample | Genotypes | Haplotypes | |||||||
---|---|---|---|---|---|---|---|---|---|
N Individuals | H1/H1 N (%) | H1/H2 N (%) | H2/H2 N (%) | Genotype vs. controlsb | N Alleles | H1 N (%) | H2 N (%) | Haplotypes vs. controls | |
FTLD | 59 | 47 (79.7) | 11 (18.6) | 1 (1.7) | P = 0.018a | 118 | 105 (89.0) | 13 (11.0) | P = 0.028a |
EoAD | 122 | 98 (80.3) | 24 (19.7) | 0 | P = 0.006a | 244 | 220 (90.2) | 24 (9.8) | P = 0.029a |
Controls | 198 | 180 (90.9) | 15 (7.6) | 3 (1.5) | 396 | 375 (94.7) | 21 (5.3) |