Genotypes | ||||||
---|---|---|---|---|---|---|
ε2/ε2 | ε2/ε3 | ε2/ε4 | ε3/ε3 | ε3/ε4 | ε4/ε4 | |
Odds Ratio (376 AD patients; 561 control individuals) | 0.7 | 0.9 | 3.2 | 1 | 4.2 | 12.9 |
CI | 0.01–7.57 | 0.51–1.41 | 1.67–6.18 | Ref | 2.98–5.89 | 6.64–26.68 |
p value | 1.00 | 0.62 | < 0.001 | < 0.001 | < 0.001 | |
Odds Ratio, AD patients with no family history of dementia (n = 149) | 1.1* | 0.7 | 2.8 | 1 | 2.9 | 8.1 |
CI | 0.00–0.16 | 0.34–1.47 | 1.17–6.44 | Ref | 1.83–4.58 | 3.53–19.18 |
p value | 1.00 | 0.47 | 0.021 | < 0.001 | < 0.000 | |
Odds Ratio, AD patients with first degree relative with dementia (n = 213) | 1.7 | 1.0 | 4.0 | 1 | 5.9 | 18.7 |
CI | 0.03–17.27 | 0.47–1.89 | 1.79–8.86 | Ref | 3.88–9.15 | 8.97–41.40 |
p value | 1.0 | 1.0 | < 0.001 | < 0.001 | < 0.001 |