Table 1 Disease characteristics of monofocal vs multifocal CIS patients
All | Monofocal | Multifocal | p-value* | |
|---|---|---|---|---|
N | 468 (100%) | 246 (53%) | 222 (47%) | |
Sex – % of females | 71% | 66% | 76% | 0.0325 † |
Age, median (quartiles) | 30 (24–37) | 29 (24–37) | 31 (25–37) | 0.0820 ‡ |
Steroid treatment – % | 71% | 72% | 70% | 0.6835† |
EDSS (screening), median (quartiles) | 2 (1–2.5) | 1.5 (1–2) | 2 (1.5–2.5) | < 0.0001 ‡ |
CSF positive of samples taken – % | 267/314 85% (57%) | 149/176 85% (61%) | 118/138 86% (53%) | 0.8745† |
Number of T2 lesions, median (quartiles) | 17 (7–38) | 16 (6–36) | 21 (8–41) | 0.0182 ‡ |
At least one Gd-enhancing lesion – % | 42% | 42% | 43% | 0.9254† |
At least one T1 hypointense lesion – % | 68% | 63% | 73% | 0.0300 † |