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Table 2 Disease course of monofocal vs. multifocal placebo patients after the CIS

From: MRI characteristics are predictive for CDMS in monofocal, but not in multifocal patients with a clinically isolated syndrome

 

All

Monofocal

Multifocal

p-value*

N

176

93

83

 

CDMS %* over 2 years

45%

47%

44%

0.7052†

Median annualized cumulative number of NALs over the study (quartiles)

3.2

(0.96–10.4)

3.0

(0.5–9.4)

3.6

(1.0–12.5)

0.4698‡

  1. *Compares monofocal vs. multifocal patients
  2. NAL: newly active lesion
  3. CDMS: clinically definite MS
  4. † Kaplan-Meier estimate at day 720, Log rank test
  5. ‡Wilcoxon test
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BMC Neurology

ISSN: 1471-2377

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