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Table 1 Table 1 Statistical comparison between different areas in AD patients ( both in baseline and follow up) and HVs when using different methods.

From: Masked-Volume-Wise PCA and "reference Logan" illustrate similar regional differences in kinetic behavior in human brain PET study using [11C]-PIB

Paired t-test, two-tailed

P value

Mean of differences

SNR, MVW-PCA vs. Ref. Logan, base line

0.0389

1.245

SNR, MVW-PCA vs. Ref. Logan, follow-up

0.4462

0.1021

SNR, MVW-PCA vs. Ref. Logan, HVs

0.0078

1.734

  1. Results obtained performing paired t-test between the ROIs from the frontal and parietal cortices (Fsin, Fdx, Psin and Pdx) in images generated using MVW-PCA and reference Logan.