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Table 2 Comparisons of CSF neural biomarkers across groups.

From: Amyloid and tau cerebrospinal fluid biomarkers in HIV infection

  sAPPα sAPPβ 1-42 t-tau p-tau
Overall ANOVA: < 0.0001 < 0.0001 < 0.0001 < 0.0001 < 0.0001
Post Hoc Comparisons:      
   ADC vs NA < 0.001 < 0.001 ns < 0.05 ns
   OIs vs NA < 0.001 < 0.001 < 0.001 ns ns
   ADC vs OIs ns ns ns ns ns
   NA vs Cont y ns ns ns ns ns
   AD vs Cont o ns ns < 0.01 < 0.001 < 0.001
   AD vs ADC < 0.001 < 0.001 ns < 0.01 < 0.001
   Cont y vs Cont o < 0.05 ns ns ns < 0.01
  1. ns = not significant
  2. * All results were also compared using non-parametric Kruskal-Wallis test that yielded similar results. Statistical tests were also conducted with age adjustment, which did not change any of the results reported above, except for that differences between younger and older controls disappeared.