From: Amyloid and tau cerebrospinal fluid biomarkers in HIV infection
sAPPα | sAPPβ | Aβ1-42 | t-tau | p-tau | |
---|---|---|---|---|---|
Cutoff value: | < 333 ng/mL | < 205 ng/mL | < 450 ng/L | > 300 ng/L | < 60 ng/L |
All HIV+ subjects | |||||
Sensitivity | 90,5 | 90,5 | 57,1 | 64,0 | 100,0 |
Specificity | 56,3 | 58,4 | 47,7 | 61,3 | 4,6 |
ROC curve AUC | 0,61 | 0,68 | 0,54 | 0,70 | 0,65 |
HIV+ excluding OIs | |||||
Sensitivity | 90,5 | 90,5 | 42,9 | 64,0 | 100,0 |
Specificity | 85,0 | 90,0 | 72,5 | 67,6 | 5,0 |
ROC curve AUC | 0,88 | 0,95 | 0,57 | 0,74 | 0,70 |