From: Autosomal recessive limb-girdle muscular dystrophies in the Czech Republic
Litera-ture | Population | Number of patients analysed in the study | Number and percentage of patients with LGMD2A | Number and percentage of patients with LGMD2I | Number and percentage of patients with LGMD2D | Number and percentage of patients with LGMD2L |
---|---|---|---|---|---|---|
This study | Czech | 218 LGMD2 probands | 71 (67 had two mutations, 4 one); 32.6% | 9; 4.1% | 6; 2.8% | 3; 1.4% |
[28] | Italy | 190 LGMD probands | 59; 31.1% | 14; 7.4% | 16; 8.4% | 4; 2.1% |
[2] | Italy | 155 LGMD probands | 44 (30 had two mutations, 14 one); 28.4% | 10; 6.4% | 13; 8.4% | NI |
[32] | Italy | 550 patients with LGMD, myopathy, or asymptomatic hyperCKemia | 102; 18.5% | 16; 2.8% | 37; 6.7% | NI |
[33] | Italy | 519 patients with LGMD, myopathy, or asymptomatic hyperCKemia | 94 (76 had two mutations, 18 one); 18.1% | NI | NI | NI |
[10] | Italy | 530 patients with muscular dytrophy | 141 (104 had two mutations and 37 one); 26.6% | NI | NI | NI |
[34] | Italy | 214 probands with muscular dystrophy or myopathy | NI | 13 (9 had two mutations, 4 one); 6.1% | NI | NI |
[35] | Germany | 98 probands with LGMD2 and 102 probands with asymptomatic or minimally symptomatic hyperCKemia | NI | 7; 3.5% | NI | NI |
[29] | Denmark | 99 LGMD2 patients | 12; 12.1% | 38; 38.4% | NI | NI |
[4] | Dutch | 67 LGMD probands | 14; 20.9% | 5; 7.5% | NI | NI |
[30] | Dutch | 68 LGMD probands | NI | NI | NI | 11; 16.2% |